Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7813.011 | 0.9584 | 0.9048 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7813.011 | 1.0979 | 1.2260 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7813.011 | 0.8017 | 0.5520 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7813.011 | 0.3441 | -0.4116 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7813.011 | 0.0764 | -0.8954 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7813.011 | 0.0020 | -0.9984 | 0.8718 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7814.011 | 1.0024 | 1.0051 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7814.011 | 1.0168 | 1.0355 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7814.011 | 1.0206 | 1.0435 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7814.011 | 0.9394 | 0.8724 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7814.011 | 0.8995 | 0.7884 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7814.011 | 0.7690 | 0.5158 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7814.011 | 0.4109 | -0.2180 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7814.011 | 0.0364 | -0.9394 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7814.011 | 0.0161 | -0.9745 | 0.9472 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9254.12 | 1.1261 | 1.2251 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9254.12 | 1.1293 | 1.2306 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9254.12 | 1.0723 | 1.1293 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9254.12 | 0.9399 | 0.8917 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9254.12 | 0.9227 | 0.8607 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9254.12 | 0.7392 | 0.5247 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9254.12 | 0.2317 | -0.4619 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9254.12 | 0.0346 | -0.9025 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9254.12 | 0.0103 | -0.9670 | 1.1139 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9258.011 | 1.1186 | 1.3482 | 0.6984 |