Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9258.011 | 0.9855 | 0.9586 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9258.011 | 1.0823 | 1.2397 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9258.011 | 0.9960 | 0.9886 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9258.011 | 0.9107 | 0.7493 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9258.011 | 0.7953 | 0.4408 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9258.011 | 0.4152 | -0.4319 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9258.011 | 0.0465 | -0.9753 | 0.6984 | |
| HCC1395 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9258.011 | 0.0096 | -0.9974 | 0.6984 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7819.075 | 1.0092 | 1.0341 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7819.075 | 1.0424 | 1.1603 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7819.075 | 0.9885 | 0.9577 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7819.075 | 1.1003 | 1.3885 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 7819.075 | 1.0353 | 1.1329 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7819.075 | 1.0664 | 1.2535 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7819.075 | 0.9423 | 0.7910 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7819.075 | 0.5071 | -0.4332 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7819.075 | 0.1807 | -0.9166 | 0.5386 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7820.011 | 0.9663 | 0.9005 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7820.011 | 1.0470 | 1.1417 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7820.011 | 1.0268 | 1.0803 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7820.011 | 1.1361 | 1.4191 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7820.011 | 1.0156 | 1.0468 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7820.011 | 1.0242 | 1.0725 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7820.011 | 0.9293 | 0.7931 | 0.6709 | |
| HCC1419 | HER2amp | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7820.011 | 0.3691 | -0.5473 | 0.6709 |