Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9226.021 | 0.0454 | -0.4152 | 2.5142 | |
| HBL-100 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9226.021 | 0.0058 | -0.7415 | 2.5142 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7810.011 | 1.0041 | 1.0088 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7810.011 | 1.0662 | 1.1437 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7810.011 | 0.9658 | 0.9261 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7810.011 | 1.1130 | 1.2457 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7810.011 | 1.0650 | 1.1409 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7810.011 | 1.0891 | 1.1934 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7810.011 | 1.0679 | 1.1474 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7810.011 | 0.1422 | -0.7577 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7810.011 | 0.0642 | -0.8974 | 0.9243 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9233.12 | 1.0433 | 1.0754 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9233.12 | 1.0975 | 1.1695 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9233.12 | 1.0641 | 1.1115 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9233.12 | 1.0111 | 1.0195 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9233.12 | 1.0582 | 1.1013 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9233.12 | 0.9854 | 0.9744 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9233.12 | 0.8480 | 0.7316 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9233.12 | 0.3435 | -0.2139 | 1.1442 | |
| HCC1143 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9233.12 | 0.0772 | -0.7868 | 1.1442 | |
| HCC1187 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7811.011 | 1.0051 | 1.0235 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7811.011 | 0.9663 | 0.8501 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7811.011 | 0.9786 | 0.9042 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7811.011 | 0.9896 | 0.9531 | 0.4400 | |
| HCC1187 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7811.011 | 0.9720 | 0.8748 | 0.4400 |