Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184B5 | NM | Basal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9095.119 | 1.0213 | 1.0347 | 1.2263 | |
| 184B5 | NM | Basal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9095.119 | 1.0443 | 1.0720 | 1.2263 | |
| 184B5 | NM | Basal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9095.119 | 0.9573 | 0.9301 | 1.2263 | |
| 184B5 | NM | Basal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9095.119 | 0.7888 | 0.6481 | 1.2263 | |
| 184B5 | NM | Basal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9095.119 | 0.6003 | 0.3192 | 1.2263 | |
| 184B5 | NM | Basal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9095.119 | 0.0898 | -0.7198 | 1.2263 | |
| 184B5 | NM | Basal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9095.119 | 0.0535 | -0.8164 | 1.2263 | |
| 184B5 | NM | Basal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9095.119 | 0.0243 | -0.9033 | 1.2263 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9118.011 | 1.0024 | 1.0046 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9118.011 | 1.0333 | 1.0632 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9118.011 | 0.9745 | 0.9517 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9118.011 | 1.0205 | 1.0388 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9118.011 | 1.0089 | 1.0170 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9118.011 | 0.9058 | 0.8207 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9118.011 | 0.9268 | 0.8608 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9118.011 | 0.3724 | -0.2166 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9118.011 | 0.2097 | -0.5458 | 1.0538 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9120.021 | 1.0234 | 1.0726 | 0.6486 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9120.021 | 1.0249 | 1.0772 | 0.6486 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9120.021 | 0.9809 | 0.9415 | 0.6486 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9120.021 | 1.0258 | 1.0800 | 0.6486 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9120.021 | 1.0329 | 1.1022 | 0.6486 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9120.021 | 1.0217 | 1.0673 | 0.6486 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9120.021 | 0.9551 | 0.8631 | 0.6486 | |
| 600MPE | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9120.021 | 0.6951 | 0.1417 | 0.6486 |