Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 5000 | uM | 7787.018 | 0.3840 | -0.8398 | 0.3791 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9047.026 | 0.9702 | 0.9012 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9047.026 | 0.9674 | 0.8922 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9047.026 | 0.9182 | 0.7337 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9047.026 | 0.7897 | 0.3470 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 8 | uM | 9047.026 | 0.8116 | 0.4099 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 40 | uM | 9047.026 | 0.7679 | 0.2853 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 200 | uM | 9047.026 | 0.7913 | 0.3514 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 1000 | uM | 9047.026 | 0.0576 | -0.9832 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 5000 | uM | 9047.026 | 0.0057 | -0.9997 | 0.5972 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10002.034 | 0.9822 | 0.9474 | 0.6736 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.064 | uM | 10002.034 | 0.9539 | 0.8647 | 0.6736 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 0.32 | uM | 10002.034 | 0.9120 | 0.7444 | 0.6736 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 1.6 | uM | 10002.034 | 0.8333 | 0.5256 | 0.6736 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 8 | uM | 10002.034 | 0.8249 | 0.5028 | 0.6736 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 40 | uM | 10002.034 | 0.8170 | 0.4814 | 0.6736 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 200 | uM | 10002.034 | 0.8919 | 0.6875 | 0.6736 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 1000 | uM | 10002.034 | 0.2119 | -0.8002 | 0.6736 | ||
| 184A1 | NM | Basal | CGC-11047 | Polyamine analogue | 5000 | uM | 10002.034 | 0.0268 | -0.9907 | 0.6736 | ||
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9095.026 | 1.2301 | 1.4519 | 1.0168 | ||
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9095.026 | 1.1246 | 1.2448 | 1.0168 | ||
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9095.026 | 1.1610 | 1.3164 | 1.0168 | ||
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9095.026 | 1.0353 | 1.0694 | 1.0168 | ||
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 8 | uM | 9095.026 | 1.0699 | 1.1374 | 1.0168 | ||
| 184B5 | NM | Basal | CGC-11047 | Polyamine analogue | 40 | uM | 9095.026 | 1.0593 | 1.1167 | 1.0168 |