Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7469.074 | 0.6652 | 0.6286 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7469.074 | 0.6652 | 0.6286 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7469.074 | 0.0090 | -0.8143 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7469.074 | 0.0090 | -0.8143 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7469.074 | 0.0026 | -0.8998 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7469.074 | 0.0026 | -0.8998 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7469.074 | 0.0003 | -0.9663 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7469.074 | 0.0003 | -0.9663 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7469.074 | 0.0022 | -0.9079 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7469.074 | 0.0022 | -0.9079 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7469.074 | 0.0005 | -0.9586 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7469.074 | 0.0005 | -0.9586 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14909.203 | 0.9967 | 0.9951 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14909.203 | 0.9967 | 0.9951 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14909.203 | 0.9706 | 0.9572 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14909.203 | 0.9706 | 0.9572 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14909.203 | 1.0110 | 1.0159 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14909.203 | 1.0110 | 1.0159 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14909.203 | 0.2656 | -0.2353 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14909.203 | 0.2656 | -0.2353 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14909.203 | 0.0160 | -0.9001 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14909.203 | 0.0160 | -0.9001 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14909.203 | 0.0119 | -0.9196 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14909.203 | 0.0119 | -0.9196 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14909.203 | 0.0056 | -0.9537 | 1.3791 |