Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14731.203 | 0.1933 | -0.0285 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14731.203 | 0.1933 | -0.0285 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14731.203 | 0.0369 | -0.5308 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14731.203 | 0.0369 | -0.5308 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14731.203 | 0.0172 | -0.6644 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14731.203 | 0.0172 | -0.6644 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14731.203 | 0.0162 | -0.6735 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14731.203 | 0.0162 | -0.6735 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14731.203 | 0.0135 | -0.6979 | 2.2762 | |
| HCC1806 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14731.203 | 0.0135 | -0.6979 | 2.2762 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7452.074 | 1.0543 | 1.0710 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7452.074 | 1.0543 | 1.0710 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7452.074 | 1.0223 | 1.0293 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7452.074 | 1.0223 | 1.0293 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7452.074 | 1.0554 | 1.0724 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7452.074 | 1.0554 | 1.0724 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7452.074 | 0.1089 | -0.5368 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7452.074 | 0.1089 | -0.5368 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7452.074 | 0.0072 | -0.9227 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7452.074 | 0.0072 | -0.9227 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7452.074 | 0.0065 | -0.9275 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7452.074 | 0.0065 | -0.9275 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7452.074 | 0.0025 | -0.9619 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7452.074 | 0.0025 | -0.9619 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7452.074 | 0.0073 | -0.9224 | 1.5162 |