Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7452.074 | 0.0073 | -0.9224 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7452.074 | 0.0032 | -0.9545 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7452.074 | 0.0032 | -0.9545 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7453.074 | 1.0830 | 1.1030 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7453.074 | 1.0830 | 1.1030 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7453.074 | 1.0218 | 1.0273 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7453.074 | 1.0218 | 1.0273 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7453.074 | 1.0143 | 1.0180 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7453.074 | 1.0143 | 1.0180 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7453.074 | 0.3826 | 0.0918 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7453.074 | 0.3826 | 0.0918 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7453.074 | 0.0096 | -0.8932 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7453.074 | 0.0096 | -0.8932 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7453.074 | 0.0076 | -0.9077 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7453.074 | 0.0076 | -0.9077 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7453.074 | 0.0042 | -0.9367 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7453.074 | 0.0042 | -0.9367 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7453.074 | 0.0070 | -0.9125 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7453.074 | 0.0070 | -0.9125 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7453.074 | 0.0041 | -0.9374 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7453.074 | 0.0041 | -0.9374 | 1.5871 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7456.074 | 0.9248 | 0.9220 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7456.074 | 0.9248 | 0.9220 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7456.074 | 0.9343 | 0.9320 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7456.074 | 0.9343 | 0.9320 | 1.9647 |