Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14906.203 | 0.0217 | -0.9851 | 0.7818 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7468.074 | 1.0068 | 1.0091 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7468.074 | 1.0068 | 1.0091 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7468.074 | 0.9557 | 0.9407 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7468.074 | 0.9557 | 0.9407 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7468.074 | 0.9784 | 0.9711 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7468.074 | 0.9784 | 0.9711 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7468.074 | 0.6276 | 0.4669 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7468.074 | 0.6276 | 0.4669 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7468.074 | 0.0100 | -0.9069 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7468.074 | 0.0100 | -0.9069 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7468.074 | 0.0024 | -0.9638 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7468.074 | 0.0024 | -0.9638 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7468.074 | 0.0008 | -0.9826 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7468.074 | 0.0008 | -0.9826 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7468.074 | 0.0008 | -0.9826 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7468.074 | 0.0008 | -0.9826 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7468.074 | 0.0011 | -0.9784 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7468.074 | 0.0011 | -0.9784 | 1.5027 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7469.074 | 0.9744 | 0.9740 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7469.074 | 0.9744 | 0.9740 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7469.074 | 1.0193 | 1.0194 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7469.074 | 1.0193 | 1.0194 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7469.074 | 1.0342 | 1.0342 | 1.9843 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7469.074 | 1.0342 | 1.0342 | 1.9843 |