Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15276.203 | 0.3220 | 0.0200 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15276.203 | 0.0167 | -0.8242 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15276.203 | 0.0167 | -0.8242 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15276.203 | 0.0030 | -0.9364 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15276.203 | 0.0030 | -0.9364 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15276.203 | 0.0069 | -0.8960 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15276.203 | 0.0069 | -0.8960 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15276.203 | 0.0105 | -0.8668 | 1.6831 | |
| CAL-148 | TNBC | - | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15276.203 | 0.0105 | -0.8668 | 1.6831 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15280.203 | 1.0044 | 1.0121 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15280.203 | 1.0044 | 1.0121 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15280.203 | 0.9181 | 0.7765 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15280.203 | 0.9181 | 0.7765 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15280.203 | 0.6907 | 0.1972 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15280.203 | 0.6907 | 0.1972 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15280.203 | 0.1131 | -0.9026 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15280.203 | 0.1131 | -0.9026 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15280.203 | 0.0776 | -0.9422 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15280.203 | 0.0776 | -0.9422 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15280.203 | 0.0542 | -0.9649 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15280.203 | 0.0542 | -0.9649 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15280.203 | 0.0336 | -0.9819 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15280.203 | 0.0336 | -0.9819 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15280.203 | 0.0324 | -0.9828 | 0.7211 | |
| CAL-85-1 | TNBC | - | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15280.203 | 0.0324 | -0.9828 | 0.7211 |