Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14290.189 | 0.9814 | 0.9300 | 0.5261 | |
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14290.189 | 0.9991 | 0.9968 | 0.5261 | |
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14290.189 | 0.6084 | -0.2222 | 0.5261 | |
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14290.189 | 0.3542 | -0.7219 | 0.5261 | |
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14290.189 | 0.3175 | -0.7741 | 0.5261 | |
| SUM52PE | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14290.189 | 0.3127 | -0.7806 | 0.5261 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14179.189 | 1.0016 | 1.0074 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14179.189 | 0.9782 | 0.9016 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14179.189 | 1.0022 | 1.0099 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14179.189 | 0.9832 | 0.9239 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14179.189 | 0.9880 | 0.9455 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14179.189 | 0.9180 | 0.6439 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14179.189 | 0.0133 | -0.9999 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14179.189 | 0.0161 | -0.9998 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14179.189 | 0.0133 | -0.9999 | 0.4365 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14293.189 | 1.0362 | 1.1088 | 0.6707 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14293.189 | 1.0634 | 1.1920 | 0.6707 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14293.189 | 1.0566 | 1.1710 | 0.6707 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14293.189 | 1.0840 | 1.2555 | 0.6707 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14293.189 | 1.0583 | 1.1764 | 0.6707 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14293.189 | 0.8215 | 0.4919 | 0.6707 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14293.189 | 0.0240 | -0.9923 | 0.6707 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14293.189 | 0.0588 | -0.9707 | 0.6707 | |
| T47D | HR+ | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14293.189 | 0.0062 | -0.9990 | 0.6707 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14182.189 | 0.9856 | 0.9179 | 0.3468 |