Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14616.189 | 0.6934 | 0.5470 | 1.4258 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14616.189 | 0.0070 | -0.9383 | 1.4258 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14616.189 | 0.0088 | -0.9277 | 1.4258 | |
| HCC38 | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14616.189 | 0.0064 | -0.9421 | 1.4258 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14257.189 | 0.9721 | 0.8557 | 0.3775 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14257.189 | 0.9626 | 0.8081 | 0.3775 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14257.189 | 0.9853 | 0.9231 | 0.3775 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14257.189 | 0.9239 | 0.6219 | 0.3775 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14257.189 | 0.9596 | 0.7931 | 0.3775 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14257.189 | 0.1963 | -0.9732 | 0.3775 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14257.189 | 0.0088 | -1.0000 | 0.3775 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14257.189 | 0.0141 | -1.0000 | 0.3775 | |
| HCC70 | TNBC | Basal A | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14257.189 | 0.0156 | -1.0000 | 0.3775 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14158.189 | 0.9336 | 0.9244 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14158.189 | 0.9556 | 0.9497 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14158.189 | 0.9740 | 0.9706 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14158.189 | 1.0195 | 1.0218 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14158.189 | 0.9684 | 0.9643 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14158.189 | 0.7111 | 0.6520 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14158.189 | 0.0093 | -0.8552 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14158.189 | 0.0094 | -0.8543 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14158.189 | 0.0074 | -0.8724 | 1.7834 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14260.189 | 1.0707 | 1.0879 | 1.5886 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14260.189 | 1.1038 | 1.1282 | 1.5886 | |
| Hs 578T | TNBC | Basal B | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14260.189 | 1.0768 | 1.0953 | 1.5886 |