Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14182.189 | 0.9670 | 0.8155 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14182.189 | 0.9879 | 0.9311 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14182.189 | 0.9726 | 0.8460 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14182.189 | 0.9850 | 0.9146 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14182.189 | 0.9894 | 0.9394 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14182.189 | 0.1916 | -0.9830 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14182.189 | 0.0215 | -1.0000 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14182.189 | 0.0202 | -1.0000 | 0.3468 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14628.189 | 0.9459 | 0.8580 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14628.189 | 0.9105 | 0.7665 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14628.189 | 0.9474 | 0.8620 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14628.189 | 0.9067 | 0.7568 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14628.189 | 0.9512 | 0.8718 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14628.189 | 0.8351 | 0.5756 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14628.189 | 0.0279 | -0.9825 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14628.189 | 0.0286 | -0.9819 | 0.7555 | |
| T47DKBLUC | Unknown | Unknown | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14628.189 | 0.0326 | -0.9785 | 0.7555 | |
| UACC-812 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14227.189 | 0.9106 | 0.8579 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14227.189 | 0.9194 | 0.8720 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14227.189 | 0.9539 | 0.9271 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14227.189 | 0.9741 | 0.9592 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14227.189 | 0.8759 | 0.8021 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14227.189 | 0.8464 | 0.7541 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14227.189 | 0.4093 | -0.0096 | 1.2712 | |
| UACC-812 | HER2amp | Luminal | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14227.189 | 0.1814 | -0.4779 | 1.2712 |