Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11852.157 | 1.0090 | 1.0128 | 1.4174 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11852.157 | 0.9625 | 0.9468 | 1.4174 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 11852.157 | 0.9522 | 0.9320 | 1.4174 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 11852.157 | 0.5609 | 0.3300 | 1.4174 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 11852.157 | 0.2657 | -0.2148 | 1.4174 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 11852.157 | 0.2714 | -0.2030 | 1.4174 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 11852.157 | 0.2637 | -0.2191 | 1.4174 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10939.151 | 0.9578 | 0.9510 | 1.7384 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10939.151 | 1.0035 | 1.0040 | 1.7384 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10939.151 | 0.9557 | 0.9485 | 1.7384 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10939.151 | 1.0013 | 1.0014 | 1.7384 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10939.151 | 0.9385 | 0.9283 | 1.7384 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10939.151 | 0.9321 | 0.9207 | 1.7384 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10939.151 | 0.5265 | 0.3829 | 1.7384 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10939.151 | 0.3337 | 0.0638 | 1.7384 | |
| T47D | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10939.151 | 0.3427 | 0.0801 | 1.7384 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12608.171 | 0.9574 | 0.9199 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12608.171 | 0.9828 | 0.9676 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12608.171 | 0.9413 | 0.8895 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12608.171 | 0.9486 | 0.9032 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 0.213 | uM | 12608.171 | 0.9222 | 0.8535 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 1.07 | uM | 12608.171 | 0.9761 | 0.9551 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 5.33 | uM | 12608.171 | 0.4164 | -0.1220 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 26.7 | uM | 12608.171 | 0.5066 | 0.0556 | 1.0643 | |
| T47DKBLUC | Unknown | Unknown | XRP44X | ELK3 | MAPK | 133 | uM | 12608.171 | 0.4891 | 0.0214 | 1.0643 |