Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10580.139 | 1.0025 | 1.0054 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10580.139 | 0.9373 | 0.8678 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10580.139 | 0.9478 | 0.8898 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10580.139 | 0.9223 | 0.8362 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10580.139 | 0.9997 | 0.9994 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10580.139 | 0.8060 | 0.5922 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10580.139 | 0.5934 | 0.1519 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10580.139 | 0.5797 | 0.1239 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10580.139 | 0.6108 | 0.1876 | 0.9460 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10754.151 | 0.9704 | 0.9382 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10754.151 | 0.9609 | 0.9184 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10754.151 | 0.9162 | 0.8253 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10754.151 | 1.0056 | 1.0117 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10754.151 | 0.9212 | 0.8357 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10754.151 | 0.6484 | 0.2723 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10754.151 | 0.4377 | -0.1559 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10754.151 | 0.5372 | 0.0454 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10754.151 | 0.5036 | -0.0227 | 0.9579 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11938.157 | 0.9271 | 0.7948 | 0.6995 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11938.157 | 0.9198 | 0.7746 | 0.6995 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11938.157 | 0.9046 | 0.7330 | 0.6995 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11938.157 | 0.9823 | 0.9497 | 0.6995 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 11938.157 | 0.8108 | 0.4820 | 0.6995 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 11938.157 | 0.5844 | -0.0721 | 0.6995 | |
UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 11938.157 | 0.2530 | -0.7197 | 0.6995 |