Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 11938.157 | 0.4342 | -0.3932 | 0.6995 | |
| UACC-812 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 11938.157 | 0.2751 | -0.6840 | 0.6995 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11660.151 | 0.9955 | 0.9906 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11660.151 | 0.8928 | 0.7745 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11660.151 | 0.9685 | 0.9337 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11660.151 | 0.8986 | 0.7868 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 11660.151 | 0.9925 | 0.9841 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 11660.151 | 0.7965 | 0.5734 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 11660.151 | 0.5902 | 0.1470 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 11660.151 | 0.5869 | 0.1402 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 11660.151 | 0.6344 | 0.2378 | 0.9483 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12003.157 | 0.9785 | 0.9598 | 1.0729 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12003.157 | 0.8896 | 0.7933 | 1.0729 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12003.157 | 0.9506 | 0.9077 | 1.0729 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12003.157 | 0.8818 | 0.7787 | 1.0729 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12003.157 | 0.9332 | 0.8752 | 1.0729 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12003.157 | 0.8021 | 0.6285 | 1.0729 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12003.157 | 0.4445 | -0.0607 | 1.0729 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12003.157 | 0.4615 | -0.0272 | 1.0729 | |
| ZR-75-1 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12003.157 | 0.6106 | 0.2627 | 1.0729 | |
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11939.157 | 0.9595 | 0.9487 | 1.5908 | |
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11939.157 | 1.0031 | 1.0038 | 1.5908 | |
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11939.157 | 0.9270 | 0.9069 | 1.5908 | |
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11939.157 | 0.9736 | 0.9667 | 1.5908 | |
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 11939.157 | 0.9360 | 0.9185 | 1.5908 |