Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 11939.157 | 0.7095 | 0.6119 | 1.5908 | |
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 11939.157 | 0.4310 | 0.1783 | 1.5908 | |
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 11939.157 | 0.4974 | 0.2894 | 1.5908 | |
| ZR75B | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 11939.157 | 0.4625 | 0.2317 | 1.5908 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14191.189 | 0.9664 | 0.9771 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14191.189 | 0.9483 | 0.9646 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14191.189 | 1.0355 | 1.0236 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14191.189 | 1.0285 | 1.0190 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14191.189 | 0.8420 | 0.8875 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14191.189 | 0.2601 | 0.2710 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14191.189 | 0.0059 | -0.6454 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14191.189 | 0.0094 | -0.5838 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14191.189 | 0.0075 | -0.6146 | 2.9704 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14607.189 | 0.9590 | 0.9400 | 1.3733 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14607.189 | 0.9388 | 0.9101 | 1.3733 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14607.189 | 0.9535 | 0.9318 | 1.3733 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.0213 | uM | 14607.189 | 0.9098 | 0.8670 | 1.3733 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.107 | uM | 14607.189 | 0.9523 | 0.9300 | 1.3733 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.533 | uM | 14607.189 | 0.5641 | 0.3182 | 1.3733 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 2.67 | uM | 14607.189 | 0.0305 | -0.8425 | 1.3733 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 13.3 | uM | 14607.189 | 0.0241 | -0.8675 | 1.3733 | |
| 21MT-1 | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 66.7 | uM | 14607.189 | 0.0230 | -0.8717 | 1.3733 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000171 | uM | 14194.189 | 0.9386 | 0.9470 | 2.3616 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.000853 | uM | 14194.189 | 0.9184 | 0.9292 | 2.3616 | |
| 21NT | HER2amp | - | Z-Leu-Leu-Norvalinal | Proteasome | Proteasome | 0.00427 | uM | 14194.189 | 0.9615 | 0.9670 | 2.3616 |