Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12594.171 | 0.9948 | 0.9913 | 1.1797 | |
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12594.171 | 0.9636 | 0.9380 | 1.1797 | |
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 12594.171 | 1.0223 | 1.0377 | 1.1797 | |
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 12594.171 | 0.7747 | 0.6109 | 1.1797 | |
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 12594.171 | 0.2384 | -0.4067 | 1.1797 | |
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 12594.171 | 0.2504 | -0.3816 | 1.1797 | |
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 12594.171 | 0.2354 | -0.4131 | 1.1797 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10642.139 | 0.9734 | 0.9246 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10642.139 | 0.9447 | 0.8443 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10642.139 | 1.0199 | 1.0570 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10642.139 | 1.0288 | 1.0827 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10642.139 | 1.0202 | 1.0577 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10642.139 | 0.9426 | 0.8384 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10642.139 | 0.7474 | 0.3207 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10642.139 | 0.6601 | 0.1064 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10642.139 | 0.7011 | 0.2057 | 0.7017 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10818.151 | 1.0149 | 1.0675 | 0.4459 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10818.151 | 0.9626 | 0.8361 | 0.4459 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10818.151 | 0.9854 | 0.9351 | 0.4459 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10818.151 | 0.9762 | 0.8946 | 0.4459 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10818.151 | 1.0293 | 1.1340 | 0.4459 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10818.151 | 0.8774 | 0.4916 | 0.4459 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10818.151 | 0.7898 | 0.1781 | 0.4459 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10818.151 | 0.7751 | 0.1296 | 0.4459 | |
| MDA-MB-175-VII | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10818.151 | 0.8004 | 0.2138 | 0.4459 |