Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10519.139 | 0.9406 | 0.8832 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10519.139 | 0.8016 | 0.6094 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10519.139 | 0.4623 | -0.0628 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10519.139 | 0.4688 | -0.0499 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10519.139 | 0.4507 | -0.0861 | 1.0177 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10998.151 | 0.9751 | 0.9290 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10998.151 | 1.0220 | 1.0632 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10998.151 | 1.0212 | 1.0611 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10998.151 | 1.0267 | 1.0768 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10998.151 | 0.9698 | 0.9140 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10998.151 | 0.6763 | 0.1427 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10998.151 | 0.4204 | -0.4215 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10998.151 | 0.6375 | 0.0499 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10998.151 | 0.6497 | 0.0789 | 0.6986 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12206.157 | 0.9522 | 0.9023 | 0.9766 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12206.157 | 0.9513 | 0.9004 | 0.9766 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12206.157 | 0.9893 | 0.9781 | 0.9766 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12206.157 | 1.0298 | 1.0611 | 0.9766 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12206.157 | 0.9284 | 0.8536 | 0.9766 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12206.157 | 0.6840 | 0.3557 | 0.9766 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12206.157 | 0.3768 | -0.2639 | 0.9766 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12206.157 | 0.3825 | -0.2524 | 0.9766 | |
| MDA-MB-134-VI | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12206.157 | 0.3427 | -0.3319 | 0.9766 | |
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12594.171 | 0.9851 | 0.9747 | 1.1797 | |
| MDA-MB-157 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12594.171 | 1.0131 | 1.0222 | 1.1797 |