Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1187 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 10753.151 | 0.0721 | -0.7708 | 1.2139 | |
| HCC1187 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 10753.151 | 0.0543 | -0.8185 | 1.2139 | |
| HCC1187 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 10753.151 | 0.1518 | -0.5769 | 1.2139 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12000.157 | 0.9819 | 0.9530 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12000.157 | 0.9586 | 0.8926 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12000.157 | 1.0082 | 1.0215 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12000.157 | 1.0036 | 1.0095 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 12000.157 | 0.9598 | 0.8957 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 12000.157 | 0.6889 | 0.2304 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 12000.157 | 0.3757 | -0.4418 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 12000.157 | 0.4007 | -0.3929 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 12000.157 | 0.5512 | -0.0801 | 0.7671 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12084.157 | 0.9799 | 0.9701 | 1.3475 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12084.157 | 1.0446 | 1.0658 | 1.3475 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12084.157 | 0.8757 | 0.8124 | 1.3475 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12084.157 | 1.0875 | 1.1285 | 1.3475 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 12084.157 | 1.0084 | 1.0124 | 1.3475 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 12084.157 | 0.7854 | 0.6718 | 1.3475 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 12084.157 | 0.4632 | 0.1298 | 1.3475 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 12084.157 | 0.5987 | 0.3667 | 1.3475 | |
| HCC1395 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 12084.157 | 0.6611 | 0.4711 | 1.3475 | |
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12001.157 | 0.9577 | 0.8589 | 0.5904 | |
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12001.157 | 0.9711 | 0.9031 | 0.5904 | |
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12001.157 | 0.9363 | 0.7889 | 0.5904 | |
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12001.157 | 0.9655 | 0.8844 | 0.5904 |