Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 12098.157 | 0.9918 | 0.9875 | 1.3067 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 12098.157 | 0.9346 | 0.8990 | 1.3067 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 12098.157 | 0.6830 | 0.4939 | 1.3067 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 12098.157 | 0.6038 | 0.3594 | 1.3067 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 12098.157 | 0.7885 | 0.6675 | 1.3067 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11058.151 | 0.9369 | 0.9432 | 2.2617 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11058.151 | 0.9087 | 0.9171 | 2.2617 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11058.151 | 0.9319 | 0.9386 | 2.2617 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11058.151 | 1.0165 | 1.0145 | 2.2617 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 0.213 | uM | 11058.151 | 0.8008 | 0.8129 | 2.2617 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 1.07 | uM | 11058.151 | 0.3093 | 0.1904 | 2.2617 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 5.33 | uM | 11058.151 | 0.3529 | 0.2620 | 2.2617 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 26.7 | uM | 11058.151 | 0.3883 | 0.3164 | 2.2617 | |
| SUM229PE | TNBC | - | XRP44X | ELK3 | MAPK | 133 | uM | 11058.151 | 0.3409 | 0.2427 | 2.2617 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10695.151 | 1.0733 | 1.0981 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10695.151 | 1.0876 | 1.1170 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10695.151 | 1.0164 | 1.0222 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10695.151 | 0.9992 | 0.9989 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10695.151 | 1.0286 | 1.0386 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10695.151 | 0.1733 | -0.3893 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10695.151 | 0.2380 | -0.2431 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10695.151 | 0.2574 | -0.2019 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10695.151 | 0.2378 | -0.2435 | 1.4773 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11852.157 | 0.8724 | 0.8164 | 1.4174 | |
| SUM52PE | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11852.157 | 0.9675 | 0.9539 | 1.4174 |