Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10872.151 | 0.9724 | 0.9605 | 1.4028 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10872.151 | 1.0862 | 1.1214 | 1.4028 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 10872.151 | 0.9590 | 0.9411 | 1.4028 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 10872.151 | 0.8343 | 0.7577 | 1.4028 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 10872.151 | 0.6926 | 0.5394 | 1.4028 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 10872.151 | 0.5621 | 0.3264 | 1.4028 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 10872.151 | 0.5808 | 0.3578 | 1.4028 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12523.157 | 0.9663 | 0.9307 | 0.9728 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12523.157 | 0.9822 | 0.9634 | 0.9728 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12523.157 | 0.9641 | 0.9262 | 0.9728 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12523.157 | 0.9604 | 0.9186 | 0.9728 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 12523.157 | 0.9722 | 0.9429 | 0.9728 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 12523.157 | 0.9566 | 0.9108 | 0.9728 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 12523.157 | 0.9011 | 0.7970 | 0.9728 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 12523.157 | 0.8768 | 0.7471 | 0.9728 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 12523.157 | 0.8995 | 0.7936 | 0.9728 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12239.157 | 0.9747 | 0.9757 | 2.0946 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12239.157 | 1.0166 | 1.0158 | 2.0946 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12239.157 | 1.0693 | 1.0650 | 2.0946 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12239.157 | 1.1283 | 1.1186 | 2.0946 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 12239.157 | 0.9478 | 0.9495 | 2.0946 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 12239.157 | 0.6198 | 0.5917 | 2.0946 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 12239.157 | 0.1419 | -0.2127 | 2.0946 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 12239.157 | 0.1602 | -0.1656 | 2.0946 | |
| HCC1806 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 12239.157 | 0.1459 | -0.2021 | 2.0946 |