Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11849.157 | 0.8962 | 0.8550 | 1.4559 | |
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11849.157 | 1.0671 | 1.0912 | 1.4559 | |
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11849.157 | 0.9762 | 0.9672 | 1.4559 | |
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11849.157 | 1.0143 | 1.0196 | 1.4559 | |
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 11849.157 | 0.8864 | 0.8411 | 1.4559 | |
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 11849.157 | 1.0173 | 1.0237 | 1.4559 | |
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 11849.157 | 0.8377 | 0.7709 | 1.4559 | |
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 11849.157 | 0.7755 | 0.6796 | 1.4559 | |
| HCC1937 | TNBC | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 11849.157 | 0.8188 | 0.7434 | 1.4559 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11055.151 | 0.8857 | 0.8756 | 1.8913 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11055.151 | 0.8856 | 0.8756 | 1.8913 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11055.151 | 0.9098 | 0.9025 | 1.8913 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11055.151 | 0.9038 | 0.8959 | 1.8913 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 11055.151 | 0.8678 | 0.8556 | 1.8913 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 11055.151 | 0.2229 | -0.0955 | 1.8913 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 11055.151 | 0.1297 | -0.3209 | 1.8913 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 11055.151 | 0.2075 | -0.1292 | 1.8913 | |
| HCC1954 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 11055.151 | 0.1273 | -0.3275 | 1.8913 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10996.151 | 1.0002 | 1.0008 | 0.4801 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10996.151 | 1.0120 | 1.0503 | 0.4801 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10996.151 | 0.9501 | 0.7976 | 0.4801 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10996.151 | 1.0295 | 1.1248 | 0.4801 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10996.151 | 0.9344 | 0.7363 | 0.4801 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10996.151 | 0.3170 | -0.8172 | 0.4801 | |
| HCC2185 | TNBC | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10996.151 | 0.2494 | -0.8892 | 0.4801 |