Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7899.018 | 0.2203 | -0.0461 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7900.018 | 0.8897 | 0.7373 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7900.018 | 0.8389 | 0.6187 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7900.018 | 0.5676 | 0.0112 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7900.018 | 0.4439 | -0.2480 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7900.018 | 0.5004 | -0.1311 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7900.018 | 0.3955 | -0.3456 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7900.018 | 0.4061 | -0.3243 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7900.018 | 0.3252 | -0.4829 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7900.018 | 0.0031 | -0.9981 | 0.8304 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7902.018 | 1.2512 | 1.2549 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7902.018 | 0.7341 | 0.6950 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7902.018 | 1.3835 | 1.3795 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7902.018 | 0.6326 | 0.5653 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7902.018 | 0.3740 | 0.1816 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7902.018 | 0.3289 | 0.1029 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7902.018 | 0.3635 | 0.1636 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7902.018 | 0.3587 | 0.1554 | 1.8686 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7902.018 | 0.1743 | -0.2147 | 1.8686 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7903.042 | 1.0157 | 1.0273 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7903.042 | 1.0261 | 1.0452 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7903.042 | 0.9352 | 0.8868 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7903.042 | 0.2758 | -0.3471 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7903.042 | 0.3137 | -0.2696 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7903.042 | 0.3733 | -0.1504 | 1.1508 |