Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7897.018 | 0.9071 | 0.7821 | 0.8448 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7897.018 | 0.8516 | 0.6536 | 0.8448 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7897.018 | 0.6181 | 0.1317 | 0.8448 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7897.018 | 0.5734 | 0.0355 | 0.8448 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7897.018 | 0.6648 | 0.2335 | 0.8448 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7897.018 | 0.6497 | 0.2005 | 0.8448 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7897.018 | 0.5921 | 0.0755 | 0.8448 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7897.018 | 0.0084 | -0.9931 | 0.8448 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7898.018 | 1.0316 | 1.0559 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7898.018 | 0.9594 | 0.9279 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7898.018 | 1.0836 | 1.1475 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7898.018 | 0.8633 | 0.7556 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7898.018 | 0.4342 | -0.0454 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7898.018 | 0.3796 | -0.1528 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7898.018 | 0.3800 | -0.1519 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7898.018 | 0.4131 | -0.0866 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7898.018 | 0.2717 | -0.3702 | 1.1279 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7899.018 | 1.0457 | 1.0443 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7899.018 | 0.8652 | 0.8632 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7899.018 | 1.0402 | 1.0389 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7899.018 | 0.7361 | 0.7216 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7899.018 | 0.3890 | 0.2600 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7899.018 | 0.3457 | 0.1892 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7899.018 | 0.3689 | 0.2276 | 2.0432 | |
| MDA-MB-436 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7899.018 | 0.3672 | 0.2249 | 2.0432 |