Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7903.042 | 0.3793 | -0.1386 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7903.042 | 0.3169 | -0.2631 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7903.042 | 0.0136 | -0.9524 | 1.1508 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.00119 | uM | 9708.006 | 0.5118 | -0.3079 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.00593 | uM | 9708.006 | 0.3843 | -0.5602 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.0297 | uM | 9708.006 | 0.2632 | -0.7585 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.148 | uM | 9708.006 | 0.4906 | -0.3526 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 0.742 | uM | 9708.006 | 0.5071 | -0.3179 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 3.71 | uM | 9708.006 | 0.3352 | -0.6460 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 18.5 | uM | 9708.006 | 0.3780 | -0.5717 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 92.7 | uM | 9708.006 | 0.0004 | -1.0000 | 0.6313 | |
| MDA-MB-453 | TNBC | Luminal | Vinorelbine | TUBB | TUBB | 463 | uM | 9708.006 | 0.0004 | -1.0000 | 0.6313 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7904.018 | 1.0336 | 1.0475 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7904.018 | 0.9529 | 0.9325 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7904.018 | 1.1268 | 1.1773 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7904.018 | 0.2551 | -0.2432 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7904.018 | 0.2044 | -0.3536 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7904.018 | 0.2556 | -0.2423 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7904.018 | 0.2825 | -0.1864 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7904.018 | 0.3549 | -0.0429 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7904.018 | 0.1498 | -0.4819 | 1.4056 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7905.018 | 1.0178 | 1.0397 | 0.8988 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7905.018 | 0.7373 | 0.4249 | 0.8988 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7905.018 | 0.8898 | 0.7564 | 0.8988 | |
| MDA-MB-468 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7905.018 | 0.0789 | -0.8814 | 0.8988 |