Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7872.042 | 0.9920 | 0.9883 | 1.3632 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7872.042 | 0.6621 | 0.4780 | 1.3632 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7872.042 | 0.3563 | -0.0619 | 1.3632 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7872.042 | 0.4533 | 0.1193 | 1.3632 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7872.042 | 0.4371 | 0.0898 | 1.3632 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7872.042 | 0.4475 | 0.1088 | 1.3632 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7872.042 | 0.0268 | -0.8594 | 1.3632 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7873.042 | 0.9869 | 0.9880 | 2.1928 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7873.042 | 0.9859 | 0.9871 | 2.1928 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7873.042 | 1.0076 | 1.0070 | 2.1928 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7873.042 | 0.3564 | 0.2495 | 2.1928 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7873.042 | 0.3511 | 0.2409 | 2.1928 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7873.042 | 0.3597 | 0.2546 | 2.1928 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7873.042 | 0.3763 | 0.2808 | 2.1928 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7873.042 | 0.3678 | 0.2674 | 2.1928 | |
| MCF12A | NM | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7873.042 | 0.0133 | -0.7212 | 2.1928 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7874.018 | 0.9893 | 0.9870 | 1.6506 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7874.018 | 1.0202 | 1.0244 | 1.6506 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7874.018 | 0.9001 | 0.8765 | 1.6506 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7874.018 | 0.4356 | 0.2089 | 1.6506 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7874.018 | 0.4114 | 0.1677 | 1.6506 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7874.018 | 0.3997 | 0.1475 | 1.6506 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7874.018 | 0.3492 | 0.0573 | 1.6506 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7874.018 | 0.2812 | -0.0727 | 1.6506 | |
| MCF7 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7874.018 | 0.0106 | -0.8729 | 1.6506 |