Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7868.018 | 0.2129 | -0.0389 | 2.1110 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7868.018 | 0.1760 | -0.1218 | 2.1110 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7868.018 | 0.2058 | -0.0543 | 2.1110 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7868.018 | 0.2058 | -0.0541 | 2.1110 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7868.018 | 0.0127 | -0.7472 | 2.1110 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7870.018 | 0.9806 | 0.9826 | 2.2478 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7870.018 | 0.7171 | 0.7250 | 2.2478 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7870.018 | 1.0133 | 1.0118 | 2.2478 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7870.018 | 0.8783 | 0.8878 | 2.2478 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7870.018 | 0.1946 | -0.0344 | 2.2478 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7870.018 | 0.1837 | -0.0590 | 2.2478 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7870.018 | 0.1810 | -0.0651 | 2.2478 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7870.018 | 0.1677 | -0.0962 | 2.2478 | |
| MCF 10A | NM | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7870.018 | 0.0105 | -0.7364 | 2.2478 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7871.018 | 1.0609 | 1.1012 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7871.018 | 0.9987 | 0.9979 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7871.018 | 1.0804 | 1.1334 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7871.018 | 0.6077 | 0.3193 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7871.018 | 0.3818 | -0.1052 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7871.018 | 0.3805 | -0.1076 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7871.018 | 0.3802 | -0.1083 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7871.018 | 0.4181 | -0.0346 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7871.018 | 0.0253 | -0.9072 | 1.1973 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7872.042 | 0.9954 | 0.9932 | 1.3632 | |
| MCF 10F | NM | - | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7872.042 | 0.9343 | 0.9027 | 1.3632 |