Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7804.042 | 0.7130 | 0.7464 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7804.042 | 0.9944 | 0.9955 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7804.042 | 1.0172 | 1.0137 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7804.042 | 0.2632 | 0.1715 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7804.042 | 0.1155 | -0.1579 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7804.042 | 0.0988 | -0.2088 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7804.042 | 0.0980 | -0.2114 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7804.042 | 0.0707 | -0.3084 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7804.042 | 0.0118 | -0.6627 | 2.4955 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 9024.018 | 0.9188 | 0.9410 | 2.8306 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 9024.018 | 0.9922 | 0.9945 | 2.8306 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 9024.018 | 0.9448 | 0.9603 | 2.8306 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 9024.018 | 0.2057 | 0.1440 | 2.8306 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 9024.018 | 0.0968 | -0.1234 | 2.8306 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 0.371 | uM | 9024.018 | 0.0871 | -0.1556 | 2.8306 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 1.85 | uM | 9024.018 | 0.0780 | -0.1881 | 2.8306 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9024.018 | 0.0523 | -0.2948 | 2.8306 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 46.4 | uM | 9024.018 | 0.0064 | -0.6646 | 2.8306 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7805.018 | 1.0618 | 1.1075 | 1.1451 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7805.018 | 0.9709 | 0.9491 | 1.1451 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7805.018 | 1.0541 | 1.0942 | 1.1451 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7805.018 | 0.5440 | 0.1753 | 1.1451 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7805.018 | 0.1772 | -0.5586 | 1.1451 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7805.018 | 0.4998 | 0.0913 | 1.1451 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7805.018 | 0.4312 | -0.0406 | 1.1451 |