Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7805.018 | 0.3275 | -0.2455 | 1.1451 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7805.018 | 0.0121 | -0.9576 | 1.1451 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7807.042 | 1.0102 | 1.0100 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7807.042 | 1.0246 | 1.0241 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7807.042 | 0.9513 | 0.9513 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7807.042 | 0.2034 | -0.0890 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7807.042 | 0.1290 | -0.2726 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7807.042 | 0.1258 | -0.2815 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7807.042 | 0.1151 | -0.3125 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7807.042 | 0.1305 | -0.2683 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7807.042 | 0.0103 | -0.7909 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7808.052 | 1.0935 | 1.0733 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7808.052 | 0.9054 | 0.9216 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7808.052 | 1.0721 | 1.0568 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7808.052 | 0.1439 | -0.0834 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7808.052 | 0.0783 | -0.2827 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 0.371 | uM | 7808.052 | 0.0876 | -0.2496 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 1.85 | uM | 7808.052 | 0.0622 | -0.3459 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7808.052 | 0.0504 | -0.3990 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 46.4 | uM | 7808.052 | 0.0031 | -0.8053 | 2.4842 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000119 | uM | 7809.018 | 0.9989 | 0.9987 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.000593 | uM | 7809.018 | 1.0159 | 1.0190 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.00297 | uM | 7809.018 | 1.0692 | 1.0815 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0148 | uM | 7809.018 | 0.9536 | 0.9440 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 0.0742 | uM | 7809.018 | 0.4513 | 0.2434 | 1.6742 |