Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | Triciribine | AKT | AKT | 6.67 | uM | 7494.074 | 0.7214 | 0.2343 | 0.6767 | |
| MDA-MB-134-VI | HR+ | Luminal | Triciribine | AKT | AKT | 33.3 | uM | 7494.074 | 0.7104 | 0.2066 | 0.6767 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0000853 | uM | 7495.074 | 0.9952 | 0.9919 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.000427 | uM | 7495.074 | 0.8780 | 0.7901 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.00213 | uM | 7495.074 | 1.0010 | 1.0017 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0107 | uM | 7495.074 | 0.9497 | 0.9140 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0533 | uM | 7495.074 | 0.9444 | 0.9049 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.267 | uM | 7495.074 | 0.8037 | 0.6600 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 1.33 | uM | 7495.074 | 0.7770 | 0.6128 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 6.67 | uM | 7495.074 | 0.7226 | 0.5161 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 33.3 | uM | 7495.074 | 0.4772 | 0.0644 | 1.1729 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0000853 | uM | 7496.074 | 0.9257 | 0.8889 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.000427 | uM | 7496.074 | 0.9051 | 0.8577 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.00213 | uM | 7496.074 | 0.9193 | 0.8791 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0107 | uM | 7496.074 | 0.8852 | 0.8273 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0533 | uM | 7496.074 | 0.8660 | 0.7979 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.267 | uM | 7496.074 | 0.7218 | 0.5710 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 1.33 | uM | 7496.074 | 0.4634 | 0.1314 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 6.67 | uM | 7496.074 | 0.5293 | 0.2486 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 33.3 | uM | 7496.074 | 0.5661 | 0.3123 | 1.3504 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0000853 | uM | 7498.074 | 0.9900 | 0.9816 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.000427 | uM | 7498.074 | 1.0282 | 1.0518 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.00213 | uM | 7498.074 | 1.0018 | 1.0034 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0107 | uM | 7498.074 | 0.9738 | 0.9517 | 1.0877 | |
| MDA-MB-157 | TNBC | Basal B | Triciribine | AKT | AKT | 0.0533 | uM | 7498.074 | 0.9052 | 0.8249 | 1.0877 |