Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0000853 | uM | 7452.074 | 1.0318 | 1.0417 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.000427 | uM | 7452.074 | 1.0265 | 1.0347 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.00213 | uM | 7452.074 | 1.0136 | 1.0178 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0107 | uM | 7452.074 | 1.0089 | 1.0117 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0533 | uM | 7452.074 | 1.0208 | 1.0273 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.267 | uM | 7452.074 | 0.8927 | 0.8557 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 1.33 | uM | 7452.074 | 0.8042 | 0.7323 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 6.67 | uM | 7452.074 | 0.7080 | 0.5926 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 33.3 | uM | 7452.074 | 0.5830 | 0.4011 | 1.5162 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0000853 | uM | 7453.074 | 0.9988 | 0.9985 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.000427 | uM | 7453.074 | 1.0183 | 1.0230 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.00213 | uM | 7453.074 | 1.0524 | 1.0654 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0107 | uM | 7453.074 | 1.0383 | 1.0479 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0533 | uM | 7453.074 | 1.0022 | 1.0028 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 0.267 | uM | 7453.074 | 0.8908 | 0.8595 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 1.33 | uM | 7453.074 | 0.8060 | 0.7459 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 6.67 | uM | 7453.074 | 0.7053 | 0.6051 | 1.5871 | |
| HCC1937 | TNBC | Basal A | Triciribine | AKT | AKT | 33.3 | uM | 7453.074 | 0.5760 | 0.4128 | 1.5871 | |
| HCC1954 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.0000853 | uM | 7456.074 | 0.9387 | 0.9367 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.000427 | uM | 7456.074 | 0.9997 | 0.9997 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.00213 | uM | 7456.074 | 0.9833 | 0.9829 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.0107 | uM | 7456.074 | 1.0931 | 1.0927 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.0533 | uM | 7456.074 | 0.9002 | 0.8958 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.267 | uM | 7456.074 | 0.9034 | 0.8992 | 1.9647 | |
| HCC1954 | HER2amp | Basal A | Triciribine | AKT | AKT | 1.33 | uM | 7456.074 | 0.7516 | 0.7294 | 1.9647 |