Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1569 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.00213 | uM | 7449.074 | 0.9853 | 0.9855 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.0107 | uM | 7449.074 | 0.9642 | 0.9645 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.0533 | uM | 7449.074 | 0.9307 | 0.9306 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Triciribine | AKT | AKT | 0.267 | uM | 7449.074 | 0.8417 | 0.8374 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Triciribine | AKT | AKT | 1.33 | uM | 7449.074 | 0.7974 | 0.7892 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Triciribine | AKT | AKT | 6.67 | uM | 7449.074 | 0.7031 | 0.6816 | 2.0321 | |
| HCC1569 | HER2amp | Basal A | Triciribine | AKT | AKT | 33.3 | uM | 7449.074 | 0.6361 | 0.6008 | 2.0321 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0000853 | uM | 7450.074 | 1.0515 | 1.0455 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.000427 | uM | 7450.074 | 1.0691 | 1.0607 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.00213 | uM | 7450.074 | 0.9729 | 0.9755 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0107 | uM | 7450.074 | 0.8834 | 0.8920 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0533 | uM | 7450.074 | 0.5388 | 0.5163 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.267 | uM | 7450.074 | 0.2949 | 0.1578 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 1.33 | uM | 7450.074 | 0.2143 | 0.0036 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 6.67 | uM | 7450.074 | 0.1550 | -0.1320 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 33.3 | uM | 7450.074 | 0.0609 | -0.4285 | 2.2338 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0000853 | uM | 7451.074 | 0.9285 | 0.9330 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.000427 | uM | 7451.074 | 0.9396 | 0.9437 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.00213 | uM | 7451.074 | 0.9384 | 0.9425 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0107 | uM | 7451.074 | 0.8693 | 0.8756 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.0533 | uM | 7451.074 | 0.7684 | 0.7723 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 0.267 | uM | 7451.074 | 0.6538 | 0.6457 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 1.33 | uM | 7451.074 | 0.5053 | 0.4623 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 6.67 | uM | 7451.074 | 0.3718 | 0.2703 | 2.1799 | |
| HCC1806 | TNBC | Basal A | Triciribine | AKT | AKT | 33.3 | uM | 7451.074 | 0.2359 | 0.0309 | 2.1799 |