Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | TPCA-1 | IKK | NFKB | 2.67 | uM | 7490.093 | 0.9104 | 0.9223 | 2.3707 | |
| MCF12A | NM | Basal B | TPCA-1 | IKK | NFKB | 13.3 | uM | 7490.093 | 0.3908 | 0.3456 | 2.3707 | |
| MCF12A | NM | Basal B | TPCA-1 | IKK | NFKB | 66.7 | uM | 7490.093 | 0.2375 | 0.0905 | 2.3707 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000171 | uM | 10419.093 | 0.9670 | 0.8860 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000853 | uM | 10419.093 | 0.9958 | 0.9854 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00427 | uM | 10419.093 | 0.9804 | 0.9320 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.0213 | uM | 10419.093 | 0.9972 | 0.9901 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.107 | uM | 10419.093 | 1.0147 | 1.0518 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.533 | uM | 10419.093 | 0.9958 | 0.9854 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 2.67 | uM | 10419.093 | 0.9038 | 0.6757 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 13.3 | uM | 10419.093 | 0.7554 | 0.2245 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 66.7 | uM | 10419.093 | 0.8297 | 0.4431 | 0.5719 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.000341 | uM | 10519.1 | 0.9218 | 0.8447 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00171 | uM | 10519.1 | 0.9851 | 0.9705 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.00853 | uM | 10519.1 | 0.9491 | 0.8990 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.0427 | uM | 10519.1 | 1.0137 | 1.0271 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 0.213 | uM | 10519.1 | 0.9785 | 0.9572 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 1.07 | uM | 10519.1 | 1.0007 | 1.0014 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 5.33 | uM | 10519.1 | 0.8386 | 0.6793 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 26.7 | uM | 10519.1 | 0.7747 | 0.5522 | 1.0071 | |
| MDA-MB-134-VI | HR+ | Luminal | TPCA-1 | IKK | NFKB | 133 | uM | 10519.1 | 0.5885 | 0.1813 | 1.0071 | |
| MDA-MB-157 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000171 | uM | 7496.093 | 0.9868 | 0.9730 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.000853 | uM | 7496.093 | 0.9624 | 0.9231 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.00427 | uM | 7496.093 | 1.0101 | 1.0207 | 0.9777 | |
| MDA-MB-157 | TNBC | Basal B | TPCA-1 | IKK | NFKB | 0.0213 | uM | 7496.093 | 0.9616 | 0.9215 | 0.9777 |