Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.00128 | uM | 10473.138 | 1.0360 | 1.0558 | 1.2872 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.0064 | uM | 10473.138 | 0.9967 | 0.9949 | 1.2872 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.032 | uM | 10473.138 | 1.0282 | 1.0437 | 1.2872 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.16 | uM | 10473.138 | 0.9040 | 0.8492 | 1.2872 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.8 | uM | 10473.138 | 0.9130 | 0.8635 | 1.2872 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 4 | uM | 10473.138 | 0.9260 | 0.8841 | 1.2872 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 20 | uM | 10473.138 | 0.9719 | 0.9562 | 1.2872 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 100 | uM | 10473.138 | 0.1455 | -0.5527 | 1.2872 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.0000853 | uM | 10755.15 | 0.9514 | 0.8763 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.000427 | uM | 10755.15 | 0.8297 | 0.5747 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.00213 | uM | 10755.15 | 0.9570 | 0.8904 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.0107 | uM | 10755.15 | 0.9360 | 0.8376 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.0533 | uM | 10755.15 | 0.8501 | 0.6245 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.267 | uM | 10755.15 | 0.8460 | 0.6142 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 1.33 | uM | 10755.15 | 0.9255 | 0.8112 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 6.67 | uM | 10755.15 | 0.9444 | 0.8586 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 33.3 | uM | 10755.15 | 0.6785 | 0.2169 | 0.7807 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.0000853 | uM | 12070.16 | 1.0310 | 1.0735 | 0.8453 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.000427 | uM | 12070.16 | 1.0797 | 1.1898 | 0.8453 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.00213 | uM | 12070.16 | 0.9488 | 0.8793 | 0.8453 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.0107 | uM | 12070.16 | 1.0822 | 1.1959 | 0.8453 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.0533 | uM | 12070.16 | 0.8182 | 0.5773 | 0.8453 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 0.267 | uM | 12070.16 | 0.7614 | 0.4487 | 0.8453 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 1.33 | uM | 12070.16 | 0.8277 | 0.5990 | 0.8453 | |
| CAMA-1 | HR+ | Luminal | Tozasertib | AURK/FLT3/ABL/JAK2 | AURK | 6.67 | uM | 12070.16 | 0.9596 | 0.9048 | 0.8453 |