Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Torkinib | 0.08 | uM | 15340.211 | 0.3644 | 0.0508 | 1.5685 | |||
| T47D | HR+ | Luminal | Torkinib | 0.4 | uM | 15340.211 | 0.3354 | -0.0033 | 1.5685 | |||
| T47D | HR+ | Luminal | Torkinib | 2 | uM | 15340.211 | 0.3259 | -0.0213 | 1.5685 | |||
| T47D | HR+ | Luminal | Torkinib | 10 | uM | 15340.211 | 0.2854 | -0.1009 | 1.5685 | |||
| T47D | HR+ | Luminal | Torkinib | 50 | uM | 15340.211 | 0.2353 | -0.2049 | 1.5685 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 0.000128 | uM | 15360.211 | 0.8180 | 0.5906 | 0.8772 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 0.00064 | uM | 15360.211 | 0.7098 | 0.3530 | 0.8772 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 0.0032 | uM | 15360.211 | 0.6423 | 0.2073 | 0.8772 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 0.016 | uM | 15360.211 | 0.5756 | 0.0655 | 0.8772 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 0.08 | uM | 15360.211 | 0.5449 | 0.0009 | 0.8772 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 0.4 | uM | 15360.211 | 0.5338 | -0.0222 | 0.8772 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 2 | uM | 15360.211 | 0.5149 | -0.0617 | 0.8772 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 10 | uM | 15360.211 | 0.5155 | -0.0603 | 0.8772 | |||
| T47DKBLUC | Unknown | Unknown | Torkinib | 50 | uM | 15360.211 | 0.4593 | -0.1763 | 0.8772 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 0.000128 | uM | 15404.211 | 0.8066 | 0.3764 | 0.5754 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 0.00064 | uM | 15404.211 | 0.6876 | 0.0431 | 0.5754 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 0.0032 | uM | 15404.211 | 0.5982 | -0.1812 | 0.5754 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 0.016 | uM | 15404.211 | 0.4748 | -0.4519 | 0.5754 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 0.08 | uM | 15404.211 | 0.4175 | -0.5619 | 0.5754 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 0.4 | uM | 15404.211 | 0.3563 | -0.6673 | 0.5754 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 2 | uM | 15404.211 | 0.3260 | -0.7150 | 0.5754 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 10 | uM | 15404.211 | 0.2977 | -0.7566 | 0.5754 | |||
| UACC-812 | HER2amp | Luminal | Torkinib | 50 | uM | 15404.211 | 0.2549 | -0.8141 | 0.5754 | |||
| ZR-75-1 | HR+ | Luminal | Torkinib | 0.000128 | uM | 15346.211 | 0.6884 | 0.1153 | 0.6395 | |||
| ZR-75-1 | HR+ | Luminal | Torkinib | 0.00064 | uM | 15346.211 | 0.5055 | -0.3118 | 0.6395 |