Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1143 | TNBC | Basal A | Torkinib | 2 | uM | 15349.211 | 0.2652 | -0.3062 | 1.2538 | |||
| HCC1143 | TNBC | Basal A | Torkinib | 10 | uM | 15349.211 | 0.2186 | -0.4053 | 1.2538 | |||
| HCC1143 | TNBC | Basal A | Torkinib | 50 | uM | 15349.211 | 0.1617 | -0.5325 | 1.2538 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 0.000128 | uM | 15300.211 | 0.8671 | 0.7058 | 0.8961 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 0.00064 | uM | 15300.211 | 0.7297 | 0.4071 | 0.8961 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 0.0032 | uM | 15300.211 | 0.6478 | 0.2320 | 0.8961 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 0.016 | uM | 15300.211 | 0.5157 | -0.0448 | 0.8961 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 0.08 | uM | 15300.211 | 0.5036 | -0.0698 | 0.8961 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 0.4 | uM | 15300.211 | 0.4460 | -0.1878 | 0.8961 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 2 | uM | 15300.211 | 0.3620 | -0.3566 | 0.8961 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 10 | uM | 15300.211 | 0.1983 | -0.6713 | 0.8961 | |||
| HCC1187 | TNBC | Basal A | Torkinib | 50 | uM | 15300.211 | 0.1583 | -0.7443 | 0.8961 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 0.000128 | uM | 15350.211 | 0.8519 | 0.7120 | 1.0306 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 0.00064 | uM | 15350.211 | 0.7240 | 0.4619 | 1.0306 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 0.0032 | uM | 15350.211 | 0.5898 | 0.1983 | 1.0306 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 0.016 | uM | 15350.211 | 0.5073 | 0.0353 | 1.0306 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 0.08 | uM | 15350.211 | 0.5699 | 0.1589 | 1.0306 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 0.4 | uM | 15350.211 | 0.3227 | -0.3326 | 1.0306 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 2 | uM | 15350.211 | 0.2789 | -0.4207 | 1.0306 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 10 | uM | 15350.211 | 0.2227 | -0.5342 | 1.0306 | |||
| HCC1428 | HR+ | Luminal | Torkinib | 50 | uM | 15350.211 | 0.1853 | -0.6104 | 1.0306 | |||
| HCC1569 | HER2amp | Basal A | Torkinib | 0.000128 | uM | 15388.211 | 0.7910 | 0.7149 | 1.5247 | |||
| HCC1569 | HER2amp | Basal A | Torkinib | 0.00064 | uM | 15388.211 | 0.7067 | 0.5928 | 1.5247 | |||
| HCC1569 | HER2amp | Basal A | Torkinib | 0.0032 | uM | 15388.211 | 0.5829 | 0.4037 | 1.5247 | |||
| HCC1569 | HER2amp | Basal A | Torkinib | 0.016 | uM | 15388.211 | 0.4748 | 0.2271 | 1.5247 |