Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.175 | uM | 7505.078 | 0.8206 | 0.6925 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.874 | uM | 7505.078 | 0.7537 | 0.5752 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 4.37 | uM | 7505.078 | 0.6043 | 0.3072 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 21.8 | uM | 7505.078 | 0.2636 | -0.3510 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 109 | uM | 7505.078 | 0.1631 | -0.5672 | 1.1847 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.000279 | uM | 7896.007 | 1.0091 | 1.0162 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.0014 | uM | 7896.007 | 0.9709 | 0.9479 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.00699 | uM | 7896.007 | 1.0558 | 1.0993 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.0349 | uM | 7896.007 | 0.8346 | 0.7019 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.175 | uM | 7896.007 | 0.6116 | 0.2895 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.873 | uM | 7896.007 | 0.5088 | 0.0942 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 4.37 | uM | 7896.007 | 0.4574 | -0.0051 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 21.8 | uM | 7896.007 | 0.2697 | -0.3791 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 109 | uM | 7896.007 | 0.0698 | -0.8142 | 1.1203 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.000279 | uM | 7896.043 | 0.9729 | 0.9368 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.0014 | uM | 7896.043 | 0.9739 | 0.9391 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.00699 | uM | 7896.043 | 0.9702 | 0.9306 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.0349 | uM | 7896.043 | 0.9112 | 0.7940 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.175 | uM | 7896.043 | 0.9348 | 0.8485 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.873 | uM | 7896.043 | 0.8790 | 0.7200 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 4.37 | uM | 7896.043 | 0.7969 | 0.5338 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 21.8 | uM | 7896.043 | 0.6422 | 0.1916 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 109 | uM | 7896.043 | 0.4876 | -0.1364 | 0.8553 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.00028 | uM | 9648.121 | 1.0695 | 1.2163 | 0.6537 | |
| MDA-MB-361 | HER2amp | Luminal | Topotecan | TOP1 | TOP | 0.0014 | uM | 9648.121 | 1.0241 | 1.0743 | 0.6537 |