Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-157	TNBC	Basal B	AS-252424	PI3K	PI3K	33.3	uM	12594.165	1.1015	1.1350	1.4798
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.000171	uM	10642.141	0.9874	0.9386	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.000853	uM	10642.141	0.9933	0.9670	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.00427	uM	10642.141	1.0030	1.0150	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.0213	uM	10642.141	1.0364	1.1841	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.107	uM	10642.141	0.9762	0.8847	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.533	uM	10642.141	0.9251	0.6507	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	2.67	uM	10642.141	0.8517	0.3467	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	13.3	uM	10642.141	0.7303	-0.0780	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	66.7	uM	10642.141	0.3019	-0.8954	0.4059
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.0000853	uM	10818.153	0.9800	0.9385	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.000427	uM	10818.153	0.9082	0.7235	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.00213	uM	10818.153	0.9753	0.9241	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.0107	uM	10818.153	0.9393	0.8155	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.0533	uM	10818.153	0.9527	0.8557	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.267	uM	10818.153	0.9111	0.7320	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	1.33	uM	10818.153	0.9273	0.7796	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	6.67	uM	10818.153	0.7889	0.3862	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	33.3	uM	10818.153	0.6418	0.0076	0.6469
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.000171	uM	12126.158	1.0069	1.0231	0.5992
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.000853	uM	12126.158	0.9373	0.7951	0.5992
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.00427	uM	12126.158	1.0061	1.0204	0.5992
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.0213	uM	12126.158	1.0017	1.0058	0.5992
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.107	uM	12126.158	1.0024	1.0080	0.5992
MDA-MB-175-VII	HR+	Luminal	AS-252424	PI3K	PI3K	0.533	uM	12126.158	0.9707	0.9032	0.5992

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)