Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000427 | uM | 10998.153 | 0.9437 | 0.8501 | 0.7434 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00213 | uM | 10998.153 | 0.9733 | 0.9285 | 0.7434 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0107 | uM | 10998.153 | 1.0063 | 1.0170 | 0.7434 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0533 | uM | 10998.153 | 0.9523 | 0.8727 | 0.7434 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.267 | uM | 10998.153 | 0.9453 | 0.8541 | 0.7434 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 1.33 | uM | 10998.153 | 0.9671 | 0.9120 | 0.7434 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 6.67 | uM | 10998.153 | 0.9025 | 0.7421 | 0.7434 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 33.3 | uM | 10998.153 | 0.7971 | 0.4741 | 0.7434 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000171 | uM | 12206.158 | 0.9449 | 0.9032 | 1.1431 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.000853 | uM | 12206.158 | 0.9380 | 0.8911 | 1.1431 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.00427 | uM | 12206.158 | 1.0176 | 1.0307 | 1.1431 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.0213 | uM | 12206.158 | 0.9899 | 0.9823 | 1.1431 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.107 | uM | 12206.158 | 1.0013 | 1.0022 | 1.1431 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 0.533 | uM | 12206.158 | 0.9862 | 0.9759 | 1.1431 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 2.67 | uM | 12206.158 | 0.9206 | 0.8603 | 1.1431 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 13.3 | uM | 12206.158 | 0.6757 | 0.4194 | 1.1431 | |
| MDA-MB-134-VI | HR+ | Luminal | AS-252424 | PI3K | PI3K | 66.7 | uM | 12206.158 | 0.8848 | 0.7969 | 1.1431 | |
| MDA-MB-157 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 12594.165 | 1.0461 | 1.0618 | 1.4798 | |
| MDA-MB-157 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000427 | uM | 12594.165 | 0.9952 | 0.9934 | 1.4798 | |
| MDA-MB-157 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00213 | uM | 12594.165 | 1.0372 | 1.0500 | 1.4798 | |
| MDA-MB-157 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0107 | uM | 12594.165 | 1.1084 | 1.1441 | 1.4798 | |
| MDA-MB-157 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0533 | uM | 12594.165 | 0.9894 | 0.9857 | 1.4798 | |
| MDA-MB-157 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.267 | uM | 12594.165 | 1.0552 | 1.0740 | 1.4798 | |
| MDA-MB-157 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 1.33 | uM | 12594.165 | 0.9387 | 0.9163 | 1.4798 | |
| MDA-MB-157 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 6.67 | uM | 12594.165 | 1.0326 | 1.0438 | 1.4798 |