Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12178.135 | 0.9988 | 0.9957 | 0.5524 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12178.135 | 1.0200 | 1.0729 | 0.5524 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12178.135 | 1.0089 | 1.0325 | 0.5524 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12178.135 | 1.0472 | 1.1740 | 0.5524 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12178.135 | 0.9782 | 0.9217 | 0.5524 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12178.135 | 0.9890 | 0.9605 | 0.5524 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12291.135 | 0.9259 | 0.6879 | 0.4536 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12291.135 | 0.8843 | 0.5252 | 0.4536 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12291.135 | 1.0113 | 1.0504 | 0.4536 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12291.135 | 0.8763 | 0.4947 | 0.4536 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12291.135 | 0.9408 | 0.7481 | 0.4536 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12291.135 | 1.0252 | 1.1130 | 0.4536 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12291.135 | 0.8956 | 0.5683 | 0.4536 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12291.135 | 0.9423 | 0.7545 | 0.4536 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12291.135 | 0.8933 | 0.5594 | 0.4536 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000171 | uM | 10696.148 | 0.9619 | 0.8080 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000853 | uM | 10696.148 | 0.9558 | 0.7782 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00427 | uM | 10696.148 | 0.9675 | 0.8355 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0213 | uM | 10696.148 | 0.9139 | 0.5827 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.107 | uM | 10696.148 | 0.9342 | 0.6757 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.533 | uM | 10696.148 | 0.9716 | 0.8556 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 2.67 | uM | 10696.148 | 0.9502 | 0.7513 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 13.3 | uM | 10696.148 | 0.9648 | 0.8222 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 66.7 | uM | 10696.148 | 0.9010 | 0.5256 | 0.3850 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11855.135 | 0.9629 | 0.8852 | 0.6394 |