Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 10581.135 | 1.0387 | 1.1793 | 0.4426 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 10581.135 | 0.9679 | 0.8579 | 0.4426 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 10581.135 | 0.9712 | 0.8724 | 0.4426 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 10581.135 | 0.9603 | 0.8250 | 0.4426 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 11854.135 | 0.9962 | 0.9943 | 1.3170 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11854.135 | 0.9630 | 0.9435 | 1.3170 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11854.135 | 0.9554 | 0.9319 | 1.3170 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11854.135 | 0.9708 | 0.9555 | 1.3170 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11854.135 | 0.9394 | 0.9073 | 1.3170 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11854.135 | 0.9862 | 0.9790 | 1.3170 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11854.135 | 0.9680 | 0.9513 | 1.3170 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 11854.135 | 0.8950 | 0.8384 | 1.3170 | |
| BT-20 | TNBC | Basal A | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 11854.135 | 0.9064 | 0.8562 | 1.3170 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12056.135 | 0.9387 | 0.8694 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12056.135 | 0.9806 | 0.9586 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12056.135 | 0.9609 | 0.9165 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12056.135 | 1.0508 | 1.1088 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12056.135 | 0.8856 | 0.7567 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12056.135 | 0.9863 | 0.9708 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12056.135 | 0.9533 | 0.9003 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12056.135 | 0.8737 | 0.7315 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12056.135 | 0.8627 | 0.7081 | 0.9361 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12178.135 | 0.9805 | 0.9298 | 0.5524 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12178.135 | 1.0900 | 1.3376 | 0.5524 | |
| BT-474 | HER2amp | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12178.135 | 1.0263 | 1.0961 | 0.5524 |