Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 11855.135 | 0.9381 | 0.8097 | 0.6394 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 11855.135 | 0.9459 | 0.8334 | 0.6394 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 11855.135 | 0.9492 | 0.8433 | 0.6394 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 11855.135 | 0.9206 | 0.7574 | 0.6394 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 11855.135 | 1.0163 | 1.0511 | 0.6394 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 11855.135 | 0.9566 | 0.8660 | 0.6394 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 11855.135 | 0.9994 | 0.9982 | 0.6394 | |
| BT-483 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 11855.135 | 0.9004 | 0.6973 | 0.6394 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 12305.135 | 0.9594 | 0.9695 | 2.6998 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 12305.135 | 1.0138 | 1.0102 | 2.6998 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 12305.135 | 1.0302 | 1.0222 | 2.6998 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 12305.135 | 1.0540 | 1.0393 | 2.6998 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 12305.135 | 1.0010 | 1.0007 | 2.6998 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 12305.135 | 0.9644 | 0.9733 | 2.6998 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 12305.135 | 0.9424 | 0.9566 | 2.6998 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 12305.135 | 0.8198 | 0.8581 | 2.6998 | |
| BT-549 | TNBC | Basal B | TCS PIM-1 1 | Pim kinase | PIM | 133 | uM | 12305.135 | 0.8138 | 0.8531 | 2.6998 | |
| CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.000341 | uM | 10473.135 | 1.0074 | 1.0128 | 1.1592 | |
| CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00171 | uM | 10473.135 | 0.9630 | 0.9360 | 1.1592 | |
| CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.00853 | uM | 10473.135 | 1.1003 | 1.1718 | 1.1592 | |
| CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.0427 | uM | 10473.135 | 0.7780 | 0.6106 | 1.1592 | |
| CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 0.213 | uM | 10473.135 | 1.0032 | 1.0055 | 1.1592 | |
| CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 1.07 | uM | 10473.135 | 0.9738 | 0.9547 | 1.1592 | |
| CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 5.33 | uM | 10473.135 | 0.9766 | 0.9596 | 1.1592 | |
| CAMA-1 | HR+ | Luminal | TCS PIM-1 1 | Pim kinase | PIM | 26.7 | uM | 10473.135 | 0.9745 | 0.9560 | 1.1592 |