Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9897.002 | 0.7047 | -0.1541 | 0.4068 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9897.002 | 0.5169 | -0.6051 | 0.4068 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9897.002 | 0.4985 | -0.6389 | 0.4068 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9897.002 | 0.5091 | -0.6196 | 0.4068 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9897.002 | 0.4964 | -0.6424 | 0.4068 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9897.002 | 0.4856 | -0.6614 | 0.4068 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 12720.002 | 1.0657 | 1.1267 | 1.0368 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 12720.002 | 0.9598 | 0.9225 | 1.0368 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 12720.002 | 1.0414 | 1.0798 | 1.0368 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 12720.002 | 0.6921 | 0.4025 | 1.0368 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 12720.002 | 0.4798 | -0.0150 | 1.0368 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 12720.002 | 0.4875 | 0.0002 | 1.0368 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 12720.002 | 0.5339 | 0.0918 | 1.0368 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 12720.002 | 0.4499 | -0.0743 | 1.0368 | |
| T47D | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 12720.002 | 0.4335 | -0.1069 | 1.0368 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 0.0000853 | uM | 13070.002 | 1.0815 | 1.2090 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 0.000427 | uM | 13070.002 | 0.9779 | 0.9440 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 0.00213 | uM | 13070.002 | 1.0424 | 1.1082 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 0.0107 | uM | 13070.002 | 0.8278 | 0.5739 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 0.0533 | uM | 13070.002 | 0.5300 | -0.1058 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 0.267 | uM | 13070.002 | 0.4734 | -0.2251 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 1.33 | uM | 13070.002 | 0.4750 | -0.2217 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 6.67 | uM | 13070.002 | 0.4627 | -0.2471 | 0.7888 | |
| T47DKBLUC | Unknown | Unknown | Taxol | TUBB | TUBB | 33.3 | uM | 13070.002 | 0.4718 | -0.2283 | 0.7888 | |
| UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9913.002 | 1.0515 | 1.1552 | 0.6723 |