Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9913.002 | 0.9199 | 0.7664 | 0.6723 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9913.002 | 1.0015 | 1.0043 | 0.6723 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9913.002 | 0.7710 | 0.3584 | 0.6723 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9913.002 | 0.6325 | 0.0117 | 0.6723 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9913.002 | 0.6090 | -0.0436 | 0.6723 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9913.002 | 0.6089 | -0.0438 | 0.6723 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9913.002 | 0.6561 | 0.0684 | 0.6723 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9913.002 | 0.6001 | -0.0642 | 0.6723 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 10150.002 | 1.0658 | 1.3396 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 10150.002 | 1.0189 | 1.0945 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 10150.002 | 1.0266 | 1.1336 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 10150.002 | 0.7393 | -0.0488 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 10150.002 | 0.6369 | -0.3408 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 10150.002 | 0.6183 | -0.3874 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 10150.002 | 0.6793 | -0.2276 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 10150.002 | 0.6311 | -0.3555 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 10150.002 | 0.6015 | -0.4274 | 0.4064 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 10267.002 | 1.2284 | 2.3160 | 0.4069 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 10267.002 | 1.0871 | 1.4558 | 0.4069 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 10267.002 | 1.1342 | 1.7256 | 0.4069 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 10267.002 | 0.6578 | -0.2854 | 0.4069 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 10267.002 | 0.6598 | -0.2801 | 0.4069 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 10267.002 | 0.6378 | -0.3378 | 0.4069 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 10267.002 | 0.6709 | -0.2500 | 0.4069 | |
UACC-812 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 10267.002 | 0.6603 | -0.2788 | 0.4069 |