Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9278.002 | 1.0017 | 1.0092 | 0.3717 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9278.002 | 0.8973 | 0.4941 | 0.3717 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9278.002 | 0.7522 | -0.0705 | 0.3717 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9278.002 | 0.7580 | -0.0509 | 0.3717 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9278.002 | 0.7397 | -0.1115 | 0.3717 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9278.002 | 0.7356 | -0.1245 | 0.3717 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9278.002 | 0.7204 | -0.1724 | 0.3717 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 10019.002 | 1.0437 | 1.2308 | 0.3915 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 10019.002 | 1.0221 | 1.1151 | 0.3915 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 10019.002 | 1.0600 | 1.3210 | 0.3915 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 10019.002 | 0.8975 | 0.5170 | 0.3915 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 10019.002 | 0.9387 | 0.7015 | 0.3915 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 10019.002 | 0.8838 | 0.4586 | 0.3915 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 10019.002 | 0.9317 | 0.6692 | 0.3915 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 10019.002 | 0.7765 | 0.0482 | 0.3915 | |
HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 10019.002 | 0.7859 | 0.0807 | 0.3915 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9294.002 | 0.9970 | 0.9921 | 0.7467 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9294.002 | 1.0090 | 1.0240 | 0.7467 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 9294.002 | 1.0000 | 1.0000 | 0.7467 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 9294.002 | 0.8505 | 0.6101 | 0.7467 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 9294.002 | 0.7562 | 0.3755 | 0.7467 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 9294.002 | 0.7123 | 0.2696 | 0.7467 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 9294.002 | 0.7018 | 0.2448 | 0.7467 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 9294.002 | 0.6825 | 0.1991 | 0.7467 | |
HCC1428 | HR+ | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 9294.002 | 0.6874 | 0.2106 | 0.7467 |