Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.000341	uM	11936.144	0.9432	0.8723	0.8864
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.00171	uM	11936.144	0.9311	0.8453	0.8864
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.00853	uM	11936.144	0.9715	0.9357	0.8864
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.0427	uM	11936.144	0.8936	0.7617	0.8864
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	0.213	uM	11936.144	0.8392	0.6411	0.8864
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	1.07	uM	11936.144	0.7618	0.4713	0.8864
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	5.33	uM	11936.144	0.7469	0.4390	0.8864
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	26.7	uM	11936.144	0.5026	-0.0796	0.8864
HCC1428	HR+	Luminal	Temsirolimus	MTOR	MTOR	133	uM	11936.144	0.0197	-0.9761	0.8864
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.000341	uM	10872.144	0.9409	0.9227	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.00171	uM	10872.144	0.9411	0.9229	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.00853	uM	10872.144	0.8221	0.7618	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.0427	uM	10872.144	0.6956	0.5812	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.213	uM	10872.144	0.6579	0.5252	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	1.07	uM	10872.144	0.6298	0.4826	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	5.33	uM	10872.144	0.6614	0.5305	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	26.7	uM	10872.144	0.5393	0.3410	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	133	uM	10872.144	0.0123	-0.8843	1.5447
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.000341	uM	12523.168	0.9855	0.9680	0.9035
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.00171	uM	12523.168	0.9929	0.9843	0.9035
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.00853	uM	12523.168	0.9552	0.9010	0.9035
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.0427	uM	12523.168	0.8583	0.6889	0.9035
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	0.213	uM	12523.168	0.7942	0.5497	0.9035
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	1.07	uM	12523.168	0.7750	0.5084	0.9035
HCC1569	HER2amp	Basal A	Temsirolimus	MTOR	MTOR	5.33	uM	12523.168	0.7467	0.4475	0.9035

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)