Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 9254.002 | 0.5100 | -0.6312 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 9254.002 | 0.5124 | -0.6269 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 9254.002 | 0.5552 | -0.5435 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 9254.002 | 0.4348 | -0.7528 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 9254.002 | 0.2723 | -0.9237 | 0.3983 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0000853 | uM | 9258.002 | 0.9735 | 0.9255 | 0.7065 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.000427 | uM | 9258.002 | 0.9796 | 0.9424 | 0.7065 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.00213 | uM | 9258.002 | 1.0006 | 1.0018 | 0.7065 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0107 | uM | 9258.002 | 0.7944 | 0.4439 | 0.7065 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.0533 | uM | 9258.002 | 0.3749 | -0.5011 | 0.7065 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 0.267 | uM | 9258.002 | 0.2758 | -0.6769 | 0.7065 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 1.33 | uM | 9258.002 | 0.2861 | -0.6597 | 0.7065 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 6.67 | uM | 9258.002 | 0.2513 | -0.7169 | 0.7065 | |
| HCC1395 | TNBC | Basal B | Taxol | TUBB | TUBB | 33.3 | uM | 9258.002 | 0.2026 | -0.7912 | 0.7065 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 7820.002 | 1.1074 | 1.3099 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 7820.002 | 1.0732 | 1.2097 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.00213 | uM | 7820.002 | 1.0978 | 1.2816 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0107 | uM | 7820.002 | 0.9700 | 0.9157 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0533 | uM | 7820.002 | 0.9610 | 0.8909 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.267 | uM | 7820.002 | 0.8600 | 0.6165 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 1.33 | uM | 7820.002 | 0.8591 | 0.6140 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 6.67 | uM | 7820.002 | 0.8305 | 0.5386 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 33.3 | uM | 7820.002 | 0.8602 | 0.6169 | 0.7084 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.0000853 | uM | 9278.002 | 1.0792 | 1.4553 | 0.3717 | |
| HCC1419 | HER2amp | Luminal | Taxol | TUBB | TUBB | 0.000427 | uM | 9278.002 | 1.0560 | 1.3157 | 0.3717 |