Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7518.067 | 1.2537 | 1.6862 | 0.7666 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7518.067 | 1.0407 | 1.1068 | 0.7666 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7518.067 | 0.6176 | 0.0666 | 0.7666 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7518.067 | 1.3490 | 1.9554 | 0.7666 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7518.067 | 1.0272 | 1.0713 | 0.7666 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7518.067 | 1.2198 | 1.5916 | 0.7666 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7518.067 | 0.6281 | 0.0904 | 0.7666 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7518.067 | 0.0058 | -0.9976 | 0.7666 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7518.067 | 0.0013 | -0.9997 | 0.7666 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7523.067 | 0.9763 | 0.9436 | 0.8380 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7523.067 | 0.9050 | 0.7755 | 0.8380 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7523.067 | 0.9466 | 0.8733 | 0.8380 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7523.067 | 0.9317 | 0.8381 | 0.8380 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7523.067 | 0.9265 | 0.8260 | 0.8380 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7523.067 | 0.8956 | 0.7535 | 0.8380 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7523.067 | 0.7269 | 0.3669 | 0.8380 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7523.067 | 0.0160 | -0.9856 | 0.8380 | |
| MX1 | Unknown | Unknown | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7523.067 | 0.0071 | -0.9946 | 0.8380 | |
| SK-BR-3 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7526.067 | 0.9316 | 0.9235 | 1.8189 | |
| SK-BR-3 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7526.067 | 0.9102 | 0.8992 | 1.8189 | |
| SK-BR-3 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7526.067 | 0.9741 | 0.9714 | 1.8189 | |
| SK-BR-3 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7526.067 | 0.9952 | 0.9947 | 1.8189 | |
| SK-BR-3 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7526.067 | 0.9997 | 0.9997 | 1.8189 | |
| SK-BR-3 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7526.067 | 0.9056 | 0.8939 | 1.8189 | |
| SK-BR-3 | HER2amp | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7526.067 | 0.6488 | 0.5766 | 1.8189 |