Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7511.067 | 1.0540 | 1.0957 | 1.1247 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7511.067 | 1.0894 | 1.1583 | 1.1247 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7511.067 | 1.1663 | 1.2932 | 1.1247 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7511.067 | 0.9873 | 0.9773 | 1.1247 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7511.067 | 0.6288 | 0.3241 | 1.1247 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7511.067 | 0.0057 | -0.9799 | 1.1247 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7511.067 | 1.1199 | 1.2119 | 1.1247 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7512.067 | 0.9693 | 0.9300 | 0.8735 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7512.067 | 1.0314 | 1.0721 | 0.8735 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7512.067 | 0.9889 | 0.9746 | 0.8735 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7512.067 | 1.0016 | 1.0037 | 0.8735 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7512.067 | 1.0106 | 1.0242 | 0.8735 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7512.067 | 0.9966 | 0.9922 | 0.8735 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7512.067 | 0.6386 | 0.1969 | 0.8735 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7512.067 | 0.0090 | -0.9909 | 0.8735 | |
| MDA-MB-415 | HR+ | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7512.067 | 0.0013 | -0.9990 | 0.8735 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.000427 | uM | 7517.067 | 0.9724 | 0.9597 | 1.3778 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.00213 | uM | 7517.067 | 1.0171 | 1.0247 | 1.3778 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0107 | uM | 7517.067 | 0.9766 | 0.9660 | 1.3778 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.0533 | uM | 7517.067 | 1.0129 | 1.0187 | 1.3778 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 0.267 | uM | 7517.067 | 1.0232 | 1.0335 | 1.3778 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 1.33 | uM | 7517.067 | 0.8835 | 0.8280 | 1.3778 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 6.67 | uM | 7517.067 | 0.5435 | 0.2848 | 1.3778 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 33.3 | uM | 7517.067 | 0.0073 | -0.9439 | 1.3778 | |
| MDA-MB-453 | TNBC | Luminal | Sunitinib | PDGFR/VEGFR/KIT/FLT3 | RTK | 167 | uM | 7517.067 | 1.1477 | 1.2103 | 1.3778 |